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. 2015 Mar 15;26(6):1106–1118. doi: 10.1091/mbc.E14-03-0812

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© 2015 Vilas, Krishnan, Loganathan, et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 1: — The cytosolic C- terminus of AQP1 has two CAII binding motifs. Examination of the human AQP1 amino acid sequence identified two consensus carbonic anhydrase binding (CAB) sites in the cytosolic C-terminus. (A) Sequence alignment of the CABs found in AQP1 genes in the indicated species. CAB1 is depicted in blue and CABII in red throughout. (B) Comparison of the same region of the other aquaporins does not reveal this motif.