Table 2.
Gene | SNP | SBP | DBP | MAP |
---|---|---|---|---|
Codominant | ||||
SCNN1A | rs13306613 | 0.347 | 2.82×10−5 b | 0.029 |
rs11064153 | 0.055 | 0.054 | 0.038 | |
SCNN1G | rs4421986 | 0.571 | 0.292 | 0.020 |
rs5735 | 0.047 | 0.015 | 0.016 | |
rs4401050 | 0.067 | 0.048 | 0.020 | |
rs4499238 | 0.037 | 0.322 | 0.122 | |
SCNN1B | rs6497659 | 0.132 | 0.031 | 0.038 |
rs7205273 | 0.061 | 0.057 | 0.033 | |
rs12447134 | 4.63×10−4 b | 0.010 | 1.61×10−3 | |
rs63982 | 0.011 | 0.052 | 0.020 | |
rs250567 | 0.176 | 8.65×10−3 | 0.024 | |
Dominant | ||||
SCNN1A | rs11064153 | 0.030 | 0.061 | 0.032 |
SCNN1G | rs4073291 | 0.029 | 0.086 | 0.039 |
rs5735 | 0.014 | 0.018 | 8.45×10−3 | |
SCNN1B | rs6497659 | 0.049 | 8.85×10−3 | 0.011 |
rs12447134 | 4.78×10−3 | 0.047 | 0.014 | |
Recessive | ||||
SCNN1A | rs13306613 | 0.292 | 2.51×10−3 | 0.028 |
SCNN1G | rs5735 | 0.404 | 0.030 | 0.077 |
rs4299163 | 0.293 | 0.028 | 0.072 | |
rs4401050 | 0.099 | 0.054 | 0.029 | |
rs4499238 | 0.041 | 0.191 | 0.089 | |
SCNN1B | rs7205273 | 0.028 | 0.018 | 0.011 |
rs239345 | 0.048 | 0.043 | 0.028 | |
rs12447134 | 1.43×10−3 | 9.12×10−3 | 2.67×10−3 | |
rs63982 | 3.51×10−3 | 0.015 | 5.18×10−3 | |
rs250567 | 0.080 | 0.041 | 0.038 |
Adjustment for age, gender, body mass index, room temperature of BP measurement, and field center;
Statistically significant after Bonferroni correction.