Table 1. Children with Group A Streptococcal bacteremia, 1992-2012.

Patient characteristics	Total N=86 (%)
Female	41 (48%)
Age distribution
<1 year	14 (16%)
1-4 years	35 (41%)
5-9 years	20 (23%)
10-17 years	17 (20%)
Co-morbid disease	30 (35%)
Oncologic*	9 (30%)
Cardiac disease	5 (17%)
Hemangioama/cystic hygroma	4 (13%)
Nephrotic syndrome	3 (10%)
Connective tissue disease	2 (7%)
Other**	7 (23%)
Immunosuppression due to underlying disease or medications	17 (20%)
Syndrome associated with GAS bacteremia
Bacteremia without a source	26 (30%)
Bacteremia with concomitant focal infections****, including:	51 (59%)
Skin and soft tissue infections	41 (48%)
Cellulitis	24 (28%)
Myositis	10 (12%)
Adenitis	9 (11%)
Abscess/phlegmon	7 (8%)
Thrombophlebitis	4 (5%)
Fasciitis (non-necrotizing)	3 (4%)
Tissue Necrosis	3 (4%)
Bone/Joint infections	22 (26%)
Osteomyelitis	15 (17%)
Septic arthritis	11 (13%)
Pneumonia	8 (9%)
Necrotizing fasciitis (NF)	3 (4%)
Meningitis	2 (2%)
Empyema	2 (2%)
Mediastinitis	1 (1%)
Epiglottitis	1 (1%)
Peritonitis	1 (1%)
Pericarditis	1 (1%)

^*Oncologic diagnoses included leukemia (7), rhabdomyosarcoma (1), and myelodysplastic syndrome (1)

^**Other diagnoses included Down's syndrome (2), encephalopathy (2), prematurity (1), short gut syndrome (1), recent tonsillectomy (1), and recent spinal rod placement (1)

^***28 patients had multiple foci of infection and therefore adding the percentages will result in a number greater than 100

^****9 patients (11%) with focal infections had STSS