Fig 3.
Tandem mass spectrometry (MS/MS) of derivatized DON – (A) Collision induced dissociation of DON after derivatization with acidified butanol – DON was derivatized with n-butanol containing 3N HCl and analyzed by LC-MS/MS. The resulting product ions of 162.03 and 116.03 match the loss of the butyl ester and the radical formed after the loss of the entire carboxyl-ester moiety. These product ions are consistent with the expected DON derivative structure. (B) Collision induced dissociation of DON after derivatization with 3N HCl – DON was derivatized with 3N HCl without butanol and analyzed by LC-MS/MS. The resulting product ion of 116.03 is consistent with the expected DON derivative structure in the absence of butanol.