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In vitro cumulative percent release of rifapentine from RPMs with different rifapentine content in PBS (0.2 M, pH 7.4).
Note: Squares: RPMs20 (8.04%); circles: RPMs50 (17.16%); triangles: RPMs100 (23.93%). RPMs20, RPMs50, and RPMs100 denote rifapentine-loaded PLGA microspheres with 20, 50, and 100 mg of rifapentine in formula, respectively.
Abbreviations: RPMs, rifapentine-loaded PLGA microspheres; PLGA, poly(lactic acid-co-glycolic acid); PBS, phosphate-buffered saline.
