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. 2015 Mar 5;9:1359–1366. doi: 10.2147/DDDT.S78407

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© 2015 Wu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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The MIC of RPMs with different rifapentine content against Staphylococcus aureus strains.

Notes: Red diamond: the lowest antibacterial agent concentration that can completely inhibit the growth of the bacterium as detected by the naked eye. (A) RPMs100 (23.93%), (B) RPMs50 (17.16%), (C) RPMs20 (8.04%). RPMs20, RPMs50, and RPMs100 denote rifapentine-loaded PLGA microspheres with 20, 50, and 100 mg of rifapentine in formula, respectively.

Abbreviations: MIC, minimal inhibitory concentration; RPMs, rifapentine-loaded PLGA microspheres; PLGA, poly(lactic acid-co-glycolic acid).