Table 3.
Regression coefficients for the association between selected clinical characteristics and brachial artery reactivity in 34 familial dysautonomia subjects with afferent autonomic failure and 34 healthy control subjects
| Characteristic | FD subjects (n = 34) | Healthy control subjects (n = 34) | ||
|---|---|---|---|---|
| r | P value | r | P value | |
| Age, y | −0.25 | 0.15 | −0.19 | 0.29 |
| Sex | −0.10 | 0.53 | −0.09 | 0.63 |
| Body surface area, m2 | −0.03 | 0.86 | −0.20 | 0.26 |
| Supine systolic blood pressure, mm Hg | 0.08 | 0.68 | −0.24 | 0.30 |
| Supine diastolic blood pressure, mm Hg | 0.03 | 0.88 | −0.34 | 0.15 |
| Supine mean blood pressure, mm Hg | 0.02 | 0.92 | −0.35 | 0.15 |
| Orthostatic change in systolic blood pressure, mm Hg | 0.07 | 0.68 | NA | NA |
| Blood urinary nitrogen, mg/dl | −0.54 | 0.002 | −0.38 | 0.12 |
| Serum creatinine, mg/dl | −0.46 | 0.008 | −0.58 | 0.01 |
| Estimated glomerular filtration rate, ml/min | 0.62 | <0.001 | 0.06 | 0.49 |
| Blood glucose, mg/dl | −0.11 | 0.60 | −0.30 | 0.23 |
| Hemoglobin, g/100 ml | −0.07 | 0.71 | −0.46 | 0.06 |
Abbreviations: FD, familiar dysautonomia; NA, not available.