Table 3.
Cumulative Sputum Culture Conversion by Selected Characteristics (N = 119)
Covariate | Cumulative Culture Conversion |
P Value | |||
---|---|---|---|---|---|
12 wks |
24 wks |
||||
n/N | % | n/N | % | ||
OVERALL | 30/119 | 25 | 87/119 | 73 | … |
Group | |||||
Pre-test implementation | 5/68 | 7 | 43/68 | 63 | <.01 |
Post-test implementation | 25/51 | 49 | 44/51 | 86 | |
Gender | |||||
Male | 17/82 | 21 | 58/82 | 71 | .20 |
Female | 13/37 | 35 | 29/37 | 78 | |
BMI (kg/m2) | |||||
≤18.5 | 10/31 | 32 | 20/31 | 65 | .60 |
>18.5 | 20/88 | 23 | 67/88 | 76 | |
Tuberculosis history | |||||
Yes | 12/48 | 25 | 31/48 | 65 | .18 |
No | 18/71 | 25 | 56/71 | 79 | |
Diabetes mellitus | |||||
Yes | 3/15 | 20 | 12/15 | 80 | .74 |
No | 27/104 | 26 | 75/104 | 72 | |
Hepatitis C | |||||
Yes | 2/9 | 22 | 4/9 | 44 | .16 |
No | 28/110 | 26 | 83/110 | 76 | |
Cavitary disease | |||||
Yes | 3/21 | 14 | 12/21 | 57 | .11 |
No | 27/98 | 28 | 75/98 | 77 | |
XDR | |||||
Yes | 0/7 | 0 | 5/7 | 71 | .63 |
No | 30/112 | 27 | 82/112 | 73 | |
Ofloxacin resistance | |||||
Yes | 0/13 | 0 | 6/13 | 46 | .03 |
No | 30/106 | 28 | 81/106 | 76 | |
Capreomycin or kanamycin resistance | |||||
Yes | 14/42 | 33 | 32/42 | 76 | .36 |
No | 16/77 | 21 | 55/77 | 71 | |
Initial treatment with kanamycin | |||||
Yes | 20/68 | 29 | 52/68 | 77 | .11 |
No | 10/51 | 20 | 35/51 | 69 | |
Treatment interruption | |||||
Yes | 13/46 | 28 | 34/46 | 74 | .72 |
No | 17/73 | 23 | 53/73 | 73 |
Abbreviations: BMI, body mass index; XDR, extensively drug-resistant.