Table 1.
Maternal Characteristics by Receipt of H1N1 Influenza Vaccine During Pregnancy
| Characteristic | All (N = 3327) | H1N1 Vaccine (n = 1125) | No Vaccine (n = 1581) | P Value |
|---|---|---|---|---|
| Maternal age, y, mean (SD) | 31.2 (5.6) | 31.5 (5.3) | 31.0 (5.7) | .01* |
| Asthma | 120 (4.0) | 44 (4.2) | 51 (3.5) | .38 |
| Maternal diabetes | 476 (15.7) | 169 (16.2) | 226 (15.6) | .72 |
| Multiple birth | 181 (5.4) | 60 (5.3) | 91 (5.8) | .64 |
| Cardiovascular disease | 183 (6.0) | 55 (5.3) | 82 (5.7) | .66 |
| Hypertension during pregnancy | 507 (15.2) | 162 (14.4) | 236 (14.9) | .70 |
| Any pregnancy complicationa | 1921 (57.7) | 602 (53.5) | 957 (60.5) | <.01* |
| Born within KP Georgia (vs KP Mid-Atlantic) | 1004 (30.2) | 286 (28.5) | 597 (59.5) | <.01* |
| Black race (subcohort) | 327 (43.1) | 62 (36.5) | 230 (46.4) | .03 |
*Indicates significant P value.
Data are No. (%) unless otherwise specified. Asthma, diabetes, and cardiovascular disease reported for births with available comorbidity data (n = 3039), including 1046 births exposed to H1N1 vaccine and 1447 births exposed to no vaccine. Black race is reported for births with available maternal race data (n = 759), including 170 births exposed to H1N1 vaccine and 496 births exposed to no vaccine.
Abbreviations: KP, Kaiser Permanente; SD, standard deviation.
a Includes fetal abnormality affecting maternal management; fetal or placental problems affecting maternal management; polyhydramnios; oligohydramnios, PROM, amnionitis; antepartum hemorrhage, abruptio placentae, and placenta previa; and antepartum complications.