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. 2015 Mar 3;6(2):e00080-15. doi: 10.1128/mBio.00080-15

TABLE 1 .

Comparison of the antimicrobial susceptibility and bacterial fitness of temporal and phylogenetic groupsa

Group (no. of isolates tested) MIC in µg/mL
Bacterial Fitness
Vancomycin Teicoplanin Daptomycin Doubling Time (mins)
Isolates recovered during 1980s (19) 1.09 0.81 0.24 39.35
Isolates recovered after 1990 (44) 1.45 1.49 0.51 45.62
P = 0.003 P < 0.001 P < 0.001 P < 0.001
Phylogenetic Clade 1 (38) 1.18 0.97 0.35 43.90
Phylogenetic Clade 2 (25) 1.59 1.79 0.52 43.46
P < 0.001 P < 0.001 P = 0.021 P = 0.790
Clade 1 isolates recovered during 1980s (19) 1.09 0.81 0.24 39.35
Clade 1 isolates recovered after 1990 (19) 1.28 1.17 0.50 48.46
P = 0.121 P = 0.057 P = 0.013 P < 0.001
a

Each value is the mean result of the respective group. P values were determined with a Welsh two-sample t test with log transformations applied to MIC data prior to comparison.