FIG. 8.

Effects of prenatal exposure to CrVI on the expression of Xpnpep2 (A–C), Col1 (D–F), Col3 (G–I), and Col4 (J–L) proteins in the PND 1 ovaries. Ovaries from PND 1 pups (F1) were processed for IHC and the integrated optical density (IOD) of staining was quantified using Image ProPlus software. The width of field for each image is 220 or 350 μm. Arrowheads indicate germ cells or oocytes (OC); arrows indicate ovigerous cord basal lamina (BL) of the follicles. An ellipse indicates a GCN. Each value represents the mean ± SEM of 15–18 ovaries. *P < 0.05, control vs. CrVI.