FIG. 9.

Effects of prenatal exposure to CrVI on the expression of Xpnpep2 (A–C), Col1 (D–F), Col3 (G–I), and Col4 (J–L) proteins in the PND 4 ovaries. Ovaries from PND 4 pups (F1) were processed for IHC and the integrated optical density (IOD) of staining was quantified using Image ProPlus software. The width of field for each image is 220 or 350 μm. Each value represents the mean ± SEM of 20–24 ovaries. Arrows indicate basal lamina (BL) of the follicle. A circle or ellipse indicates a primordial follicle (PRM) or primary follicle (PF). OC, oocyte; GC, granulosa cell. *P < 0.05, control vs. CrVI.