Table 3.
Clinical trials using aPDT as treatment.
| Disease | Fungus species | aPDT | Additional treatment | Final outcome | Reference |
|---|---|---|---|---|---|
| Pityriasis versicolor | Malassezia species | ALA-PDT | – | Complete clearance | Kim and Kim (2007) |
| Onychomycosis | T. rubrum | ALA-PDT | Treatment with 40% urea ointment for 12 h prior to aPDT | Clinical and microbiological cures | Piraccini et al. (2008) |
| Onychomycosis | – | ALA and red light | – | Significant improvement after treatments | Sotiriou et al. (2010) |
| Malassezia infection | M. folliculitis | MAL-PDT | Control of the tissue fungal burden | Lee et al. (2010) | |
| Onychomycosis | F. oxysporum and A. terreus | MAL 16% and LED | Treatment with 40% urea ointment for 12 h prior to aPDT | Clinical and microbiological cures | Gilaberte et al. (2011) |
| Denture stomatitis (DS) | Candida species | Photogem® and LED | – | Mycological cultures | Mima et al. (2012) |
| Sporotrichosis | S. schenckii complex | MB-PDT | Low dose itraconazole | Complete microbiological and clinical response | Gilaberte et al. (2014) |
| Chromoblastomycosis | F. pedrosoi and C. carrionii | MB and LED light | Control of the tissue fungal burdens | Lyon et al. (2011) |