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. 2015 Mar 13;6:202. doi: 10.3389/fmicb.2015.00202

Table 3.

Clinical trials using aPDT as treatment.

Disease Fungus species aPDT Additional treatment Final outcome Reference
Pityriasis versicolor Malassezia species ALA-PDT Complete clearance Kim and Kim (2007)
Onychomycosis T. rubrum ALA-PDT Treatment with 40% urea ointment for 12 h prior to aPDT Clinical and microbiological cures Piraccini et al. (2008)
Onychomycosis ALA and red light Significant improvement after treatments Sotiriou et al. (2010)
Malassezia infection M. folliculitis MAL-PDT Control of the tissue fungal burden Lee et al. (2010)
Onychomycosis F. oxysporum and A. terreus MAL 16% and LED Treatment with 40% urea ointment for 12 h prior to aPDT Clinical and microbiological cures Gilaberte et al. (2011)
Denture stomatitis (DS) Candida species Photogem® and LED Mycological cultures Mima et al. (2012)
Sporotrichosis S. schenckii complex MB-PDT Low dose itraconazole Complete microbiological and clinical response Gilaberte et al. (2014)
Chromoblastomycosis F. pedrosoi and C. carrionii MB and LED light Control of the tissue fungal burdens Lyon et al. (2011)