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. 2015 Jan 20;290(10):6281–6292. doi: 10.1074/jbc.M114.604546

FIGURE 5.

FIGURE 5.

Structure of sugar isomerases. A, overall structure of monomeric SagDhuI (stereo diagram). B, topology of monomeric SagDhuI. C, quaternary structure of SagDhuI. The four monomeric subunits are colored in green (chain A), red (chain B), yellow (chain A′), and blue (chain B′). Stick models indicate tartrate molecules. D, tartrate-binding residues in SagDhuI T74A. Shown is an omit map (Fo − Fc) of tartrate (gray mesh with a contour of 3σ). E, active site of SagDhuI T74A. F, ribose 5-phosphate-bound active site of clostridial RpiB (PDB code 3HEE). Subunit molecules (chains) are given in parenthesis. Atoms of carbon, nitrogen, oxygen, and phosphorus are colored in yellow, blue, red, and orange, respectively.