Skip to main content
. 2015 Jan 15;290(10):6546–6557. doi: 10.1074/jbc.M114.615716

FIGURE 7.

FIGURE 7.

Effect of integrin α1β1 on FFA metabolism. A, arterial non-esterified FFAs (NEFAs) in the basal 5-h fasted state and during the insulin clamp. B, expression of several genes implicated in the regulation of fatty acid metabolism. mRNA was extracted from 5-h fasted livers, and qPCR was performed to determine gene expression (n = 5–6/group). C and D, high resolution respirometry was performed on mechanically permeabilized liver pieces from 5-h fasted mice. Data are presented as means ± S.E. *, p < 0.05 compared with chow-fed itga1+/+ mice; §, p < 0.05 compared with HF-fed itga1+/+ mice. CSA, citrate synthase activity.