FIGURE 5.

Repression mediated by PHF6 is diminished as a result of knockdown of RBBP4. A, luciferase reporter assays of PHF6 constructs and mutants. A schematic representation of the reporter and expression vectors used in the transfection experiments is also shown. TK, thymidine kinase; LUC, luciferase; GDBD, GAL4 DNA-binding domain; FL, full-length; aa, amino acids. B, knockdown of RBBP4 reduces the repression mediated by PHF6. The quantifications represent means ± S.D. of three independent experiments.