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. 2014 Sep 15;8(6):1832–1844. doi: 10.1016/j.celrep.2014.07.055

Figure 5.

Figure 5

Concept Describing the General Relationship between the Presence of Long Terminal or Internal Disordered Segments and Protein Half-Life

Disordered segments influence protein half-life by permitting efficient initiation of degradation by the proteasome. Ubiquitination and other factors contributing to substrate targeting to the proteasome are not depicted.