Table 1.
Associations between OPN expression and clinicopathological characteristics of LSCC
| Variables | N | OPN expression | P values | |
|---|---|---|---|---|
|
| ||||
| High | Low | |||
| Age (yr) | 0.466 | |||
| <60 | 23 | 16 | 7 | |
| ≥60 | 49 | 38 | 11 | |
| Gender | 0.442 | |||
| Male | 67 | 51 | 16 | |
| Female | 5 | 3 | 2 | |
| Tobacco | 0.612 | |||
| Ever | 52 | 40 | 12 | |
| Never | 20 | 14 | 6 | |
| Alcohol | 0.475 | |||
| Ever | 47 | 34 | 13 | |
| Never | 25 | 20 | 5 | |
| Tumor sites | 0.851 | |||
| Supraglottic | 28 | 20 | 8 | |
| Glottic | 40 | 31 | 9 | |
| Infraglottic | 4 | 3 | 1 | |
| Overall stage | 0.013* | |||
| I-II | 30 | 18 | 12 | |
| III-IV | 42 | 36 | 6 | |
| Tumor differentiation | 0.014* | |||
| Well | 34 | 21 | 13 | |
| Moderate/poor | 38 | 33 | 5 | |
| Lymph node metastasis | 0.001* | |||
| Positive | 33 | 31 | 2 | |
| Negative | 39 | 23 | 16 | |
| Treatment | 0.492 | |||
| Surgery only | 31 | 22 | 9 | |
| Combined | 41 | 32 | 9 | |
*
P<0.05.