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. 2015 Jan 15;8(1):188–202.

Table 1.

The changes of paracrine cytokines in MSCs in each group

Protein information B/A (fold) C/A (fold) D/A (fold) E/A (fold) F/A (fold)
MCP-1 1.34 1.12 1.24 1.52* 1.17
TRAIL 0.81 0.46*,#,Δ 0.77 0.79 0.70
MIP-2 1.52* 1.36 1.41 0.99 1.07
CINC-2 alpha/beta 1.01 0.98 1.56* 0.97 1.01
CD106 1.12 0.79 1.06 0.88 1.07
Activin A 1.53*,Δ 1.43*,Δ 0.99 1.63*,Δ 1.32*,Δ
MDC 0.82 0.73 1.13 0.83 1.30
Adiponectin/Acrp30 0.78 0.78 1.01 1.10 1.23
IL-4 1.02 0.87 1.17 0.93 1.20
RALT/MIG-6 1.05 0.87 0.91 0.94 1.19
IL-10 1.12 1.01 1.29 1.07 1.31
Integrin alpha M beta 2 1.15 1.00 1.14 1.85*,#,Δ 3.62*,#,Δ
GM-CSF 1.22 1.06 1.28 1.06 1.30
TGF-beta3 1.02 1.01 1.11 1.08 1.44*,#,Δ
GFR alpha-2 1.28 1.03 1.24 1.09 1.32
MIP-1 alpha 1.73*,Δ 1.83*,Δ 0.89 1.42*,Δ 1.48*,Δ
IL-6 1.34 1.18 1.37 1.09 1.32
EG-VEGF/PK1 1.03 0.87 1.09 0.98 1.27
TLR4 1.14 1.00 0.84 1.07 1.52*,#,Δ
Prolactin R 0.81 0.72 1.08 0.86 1.12
Thrombospondin 1.03 1.09 1.23 1.39*,# 1.70*,#
IL-1 beta 1.07 1.12 1.50 1.25 1.48
IL-5 1.02 0.77 0.94 0.86 1.13
IP-10 1.20 1.16 1.38 1.27 1.75*,#
MIF 1.60*,#,Δ 1.08 1.04 1.27 1.72*,#,Δ
TIMP-2 1.17 0.94 0.97 1.07 2.06*,#,Δ
Insulin Degrading Enzyme 1.13 1.19 1.19 1.32 4.27*,#,Δ

A: control group; B: low-dose PMA group; C: high-dose PMA group; D: PKCε inhibiting group; E: CXCR4 antagonist group; F: PI3K inhibiting group.

*

P < 0.05 vs. the control;

#

P < 0.05 vs. group C;

Δ

P < 0.05 vs. group D.