Table 2.
Results of meta-analysis and subgroup analyses
| No. of studies | Test of association | Heterogeneity | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| OR (95% CI) | Z | P Value | Model | χ 2 | P Value | I 2 (%) | ||
| Overall | 12 | 1.65 (1.44-1.88) | 7.40 | < 0.00001 | R | 19.15 | 0.06 | 43 |
| Race | ||||||||
| Asian | 3 | 1.78 (1.49-2.12) | 6.35 | < 0.00001 | F | 0.91 | 0.63 | 0 |
| Caucasian | 8 | 2.03 (1.12-3.69) | 2.33 | 0.02 | R | 16.46 | 0.02 | 57 |
| Gender | ||||||||
| Male | 2 | 1.62 (1.29-2.03) | 4.15 | < 0.0001 | F | 0.64 | 0.42 | 0 |
| Female | 2 | 1.81 (1.27-2.57) | 3.30 | 0.001 | F | 1.28 | 0.26 | 22 |
| Glaucoma type | ||||||||
| POAG | 6 | 1.87 (1.54-2.33) | 6.09 | < 0.00001 | F | 3.79 | 0.58 | 0 |
| NTG | 5 | 3.57 (0.89-14.43) | 1.79 | 0.07 | F | 0.49 | 0.97 | 0 |
| Severity of OSAHS | ||||||||
| Mild | 3 | 2.60 (0.27-25.40) | 0.82 | 0.41 | F | 0.04 | 0.85 | 0 |
| Moderate | 2 | 5.44 (0.27-108.60) | 1.11 | 0.27 | F | 0.54 | 0.76 | 0 |
| Severe | 4 | 5.49 (1.04-33.83) | 2.01 | 0.04 | F | 0.20 | 0.91 | 0 |
POAG, primary open-angle glaucoma; NTG, normal tension glaucoma; OSAHS, obstructive sleep apnea/hypopnea syndrome; R, random-effects model; F, fixed-effects model.