Figure 5.

FAK is downregulated in Hela and C33A cells transfected with miR-7-MSCV.Relative expression of FAK mRNA by qPCR (top) and FAK protein expression by western blot (bottom) in Hela (A) and C33A cells (B) transfected with miR-7-MSCV and control vector. *P < 0.05, **P < 0.001. There were inverse correlations between miR-7 and FAK expression in 40 cervical cancer tissues (C) (r = 0.750; P < 0.05) and 17 metastatic cervical cancer tissues (D) (r = 0.820; P < 0.05) by detecting mRNA expression.