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Hypoxia stimulation induces HIF-1α activation in NRSMCs. NRSMCs were exposed to hypoxia (2% oxygen) for different durations. Real time PCR and western blot were performed to measure the mRNA (A) and protein (B and C) levels of HIF-1α in NRSMCs. *P < 0.05, **P < 0.01 vs control group.
