Table 1.

The expression of SIRT1 and Phospho-SIRT1 in colorectal cancer

Characteristics	n	Expression of SIRT1			Expression of P-SIRT1
		Positive	Negative	P value	Positive	Negative	P value
Gender				0.470			0.190
Male	32	18	14		10	22
Female	18	12	6		9	9
Age (year)				0.047			0.547
< 60	21	16	5		9	12
≥ 60	29	14	15		10	19
Grade				0.929			0.802
High-Middle	44	27	17		17	27
Low	6	3	3		2	4
TNM stage				0.018			0.405
I-II	30	14	16		10	20
III-IV	20	16	4		9	11
LN metastasis				0.341			0.285
Absent	31	17	14		10	21
Present	19	13	6		9	10
Distant metastasis				NS			NS
Absent	49	30	20		19	31
Present	1	0	0		0	0
P53 mutation				0.015			0.186
Positive	27	12	15		8	19
Negative	23	18	5		11	12
Ki67				0.108			0.011
Positive	34	23	11		17	17
Negative	16	7	9		2	14

P-SIRT1, Phospho-SIRT1; TNM, tumor node metastasis; LN, lymph node. The χ² test or Fisher’s exact test was used to evaluate the association between SIRT1 or Phospho-SIRT1 expression and clinicopathological characteristics. P value < 0.05 was considered statistically significant.