Table 1.
Demographic and baseline characteristics of HCC patients with pulmonary metastasis
| Variables | No. of patients | Proportion (%) |
|---|---|---|
| Age (median, range, years) | 56 (34-76) | |
| Sex | ||
| Male | 21 | 80.7 |
| Female | 5 | 19.3 |
| Cause of HCC | ||
| Hepatitis B virus | 23 | 88.5 |
| Hepatitis C virus | 2 | 7.7 |
| Other | 1 | 3.8 |
| Child-pugh classfication | ||
| Child class A | 19 | |
| Child class B | 7 | 73.1 |
| Cirrhosis | 26.7 | |
| Presence | 20 | 76.9 |
| Absence | 6 | 23.1 |
| ECOG performance status | ||
| 0 | 16 | 61.6 |
| 1 | 9 | 34.6 |
| 2 | 1 | 3.8 |
| AFP | ||
| < 100 | 16 | 61.5 |
| ≥ 100 | 12 | 38.5 |
| Prior therapy | ||
| No | 5 | 19.2 |
| Yes | 21 | 80.8 |
| Intrahepatic lesion | ||
| Maximum tumor diameter (cm) | 8.74 ± 3.44 | |
| Tumor number | ||
| Solitary | 11 | 42.3 |
| Multiple | 15 | 57.7 |
| Portal vein tumor thrombus | ||
| Absence | 23 | 88.4 |
| Presence | 3 | 11.6 |
| Hepatic vein tumor thrombus | ||
| Absence | 22 | 84.6 |
| Presence | 4 | 15.4 |
| Pulmonary metastasis | ||
| Number of metastasis | ||
| Solitary | 5 | 19.2 |
| Multiple | 21 | 80.8 |
| Maximum metastasis diameter (cm) | 1.99 ± 0.79 | |
| < 2 cm | 12 | 46.1 |
| ≥ 2 cm | 14 | 53.9 |
Note: AFP: alpha fetoprotein; ECOG: Eastern Cooperative Oncology Group; CR (Complete Response) represents the complete disappearance of all target lesions; PR (Partial Response) means 30% decrease in the longest diameter of target lesions; PD (Progressive Disease) corresponds to at least 20% increase in the longest diameter of target lesions; SD (Stable Disease) indicates neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD.