Table 1.
Univariate analysis of clinicopathologic variables
| Variable | No. of patients | Median survival (month) | X2 | P value |
|---|---|---|---|---|
| Gender | ||||
| Male | 122 | 23.5 | ||
| Female | 82 | 24.0 | 0.67 | 0.77 |
| Age | ||||
| < 60 | 52 | 26.1 | ||
| ≥ 60 | 152 | 22.4 | 1.14 | 0.19 |
| Surgical margin | ||||
| Negative | 153 | 26.0 | ||
| Positive | 51 | 15.1 | 4.31 | 0.03 |
| lymph node metastasis | ||||
| Negative | 75 | 24.2 | ||
| Positive | 129 | 21.2 | 5.44 | 0.02 |
| Operative procedure | ||||
| Radical | 55 | 24.7 | ||
| Palliative | 149 | 10.5 | 5.57 | 0.02 |
| CA 19-9 level | ||||
| < 37 ku/ml | 123 | 24.1 | ||
| ≥ 37 ku/m l | 81 | 23.8 | 1.634 | 0.39 |
| CEA level | ||||
| < 15 ng/ml | 68 | 22.2 | ||
| ≥ 15 ng/ml | 136 | 24.7 | 2.24 | 0.11 |
| Tumor differentiation | ||||
| Well | 112 | 26.1 | ||
| Moderate | 23 | 22.1 | ||
| Poorly | 69 | 15.6 | 13.74 | < 0.01 |
| Total bilirubin | ||||
| < 342 µmol/L | 89 | 31.2 | ||
| ≥ 342 µmol/L | 115 | 24.6 | 3.48 | 0.06 |
| Adjuvant chemotherapy | ||||
| Yes | 26 | 24.4 | ||
| No | 178 | 22.0 | 2.97 | 0.07 |
| Tumor diameter | ||||
| < 3 cm | 74 | 26.1 | ||
| 3 cm-5 cm | 77 | 23.6 | ||
| ≥ 5 cm | 53 | 19.1 | 2.54 | 0.06 |
| Combined bile duct stone | ||||
| Yes | 87 | 23.5 | ||
| No | 117 | 24.1 | 1.23 | 0.01 |
| Bismuth-Corlette classification | ||||
| I | 18 | 27.1 | ||
| II | 40 | 22.5 | ||
| IIIa | 65 | 23.1 | ||
| IIIb | 54 | 25.0 | ||
| IV | 27 | 12.0 | 2.50 | 0.06 |