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. 2015 Mar 6;10:475–487. doi: 10.2147/COPD.S75776

Table 4.

Correlationa of NiSCI scores with SGRQ, E-RS total, and FEV1b at baseline week

Six-item symptom severity scorec Overall symptoms severity scored Number of nighttime awakenings score Rescue medication score
SGRQ total score 0.58*** 0.57*** 0.45*** 0.35***
SGRQ symptoms score 0.66*** 0.60*** 0.45*** 0.39***
SGRQ impacts score 0.55*** 0.53*** 0.45*** 0.35***
E-RS total score 0.76*** 0.73*** 0.50*** 0.36***
FEV1 (trough)b −0.01 −0.04 0.01 −0.06

Notes:

a

Spearman rank order correlation coefficients

***

P<0.0001.

b

Morning predose value.

c

Average score of six symptom severity items (cough, wheezing, shortness of breath, tightness in your chest, chest congestion, and difficulty bringing up phlegm).

d

Single item on overall nighttime symptoms severity.

Abbreviations: NiSCI, Nighttime Symptoms of COPD Instrument; SGRQ, St George’s Respiratory Questionnaire; E-RS, Exacerbations of Chronic Obstructive Pulmonary Disease Tool-Respiratory Symptoms; FEV1, forced expiratory volume in 1 second.