Table 3.
Comparison between nontreated and OS-NPs-treated RBC, of the ten less abundant proteins identified in nontreated RBC
| Control RBC
|
Description | OS-NPs
|
||||
|---|---|---|---|---|---|---|
| MS/MS queries | Peptide number | Sequence coverage (%) | Sequence coverage (%) | Peptide number | MS/MS queries | |
| 1 | 1 | 3.4 | Calpain small subunit 1 | 60.8 | 12 | 63 |
| 2 | 2 | 3.4 | Heat shock protein HSP 90-alpha | 26 | 17 | 30 |
| 2 | 2 | 2 | T-complex protein 1 subunit theta | 48.5 | 28 | 63 |
| 2 | 1 | 5.2 | Proteasome subunit alpha type-7 | 42.9 | 8 | 13 |
| 2 | 2 | 5 | Transkelolase | 11.9 | 5 | 11 |
| 2 | 2 | 17.1 | Ubiquitin-conjugating enzyme E2 N | 79.6 | 10 | 28 |
| 2 | 1 | 1.4 | Plastin-2 | 18 | 9 | 19 |
| 2 | 2 | 14.1 | Hemoglobin subunit theta-1 | 17.6 | 2 | 5 |
| 3 | 2 | 13.2 | Proteasome subunit alpha type-2 | 41.5 | 6 | 11 |
| 3 | 2 | 9.5 | Proteasome subunit beta type-5 | 27.4 | 7 | 12 |
Notes: The total number of MS/MS queries, the number of different identified peptides, and the protein sequence coverage inform about the enrichment of these ten proteins in NP sample.
Abbreviations: RBC, red blood cell; NPs, nanoparticles; MS/MS, tandem mass spectrometry.