Table 4.

Results of a 2×2 mixed-model MANOVA and univariate ANOVA for BMC and BMD

Source of variance	F-value	P-value
MANOVA
Group	3.66	0.007*
Time	106.18	<0.0001*
Time × group	101.09	<0.0001*
BMC of neck of femur
Between subjects (group)	10.68	0.003**
Within subjects (time)	115.04	<0.0001**
Time × group	90.97	<0.0001**
BMD of neck of femur
Between subjects (group)	11.1	0.002**
Within subjects (time)	216.23	<0.0001**
Time × group	98.12	<0.0001**
BMC of trochanter
Between subjects (group)	11.25	0.002**
Within subjects (time)	121.7	<0.0001**
Time × group	95.18	<0.0001**
BMD of trochanter
Between subjects (group)	13.21	0.001**
Within subjects (time)	205.45	<0.0001**
Time × group	126.56	<0.0001**
BMD of Ward’s triangle
Between subjects (group)	11.87	0.002**
Within subjects (time)	149.14	<0.0001**
Time × group	93.14	<0.0001**
BMC of L2
Between subjects (group)	10.53	0.003**
Within subjects (time)	46.94	<0.0001**
Time × group	43.42	<0.0001**
BMD of L2
Between subjects (group)	10.59	0.003**
Within subjects (time)	395.63	<0.0001**
Time × group	316.95	<0.0001**
BMC of L3
Between subjects (group)	10.43	0.003**
Within subjects (time)	112.05	<0.0001**
Time × group	102.87	<0.0001**
BMD of L3
Between subjects (group)	10.89	0.003**
Within subjects (time)	95.63	<0.0001**
Time × group	64.59	<0.0001**
BMC of L4
Between subjects (group)	12.7	0.001**
Within subjects (time)	434.46	<0.0001**
Time × group	423.27	<0.0001**
BMD of L4
Between subjects (group)	12.23	0.002**
Within subjects (time)	125.99	<0.0001**
Time × group	87.74	<0.0001**

Notes:

^*Significant at α=0.05;

^**Significant with Bonferroni-corrected α=0.0045.

Abbreviations: MANOVA, multivariate analysis of variance; ANOVA, analysis of variance; BMC, bone mineral content; BMD, bone mineral density.