Model simulation of TTS membrane potential and IKir in response to voltage clamp pulses
A and C, experimental di-8-ANEPPS transients (A) and total IKir (C) recorded in a fibre bathed in 96 mm extracellular [K+]. B and D, model predictions of the average (along the radius) TTS membrane potential and total IKir. For all panels, the responses to pulses to +40, +20, −40, −80, −120 and −160 mV are represented by traces a–f, respectively. Fibre diameter, 56 μm; length, 497 μm; capacitance, 6.5 μF cm−2. See text for details.