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. 2015 Mar 6;9:1401–1417. doi: 10.2147/DDDT.S67976

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© 2015 Abu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) analysis of tumors harvested from both control mice as well as flavokawain B (50 mg/kg)-treated mice (A), and quantified (B). Histological staining of both the tumors (control and flavokawain B-treated) with hematoxylin and eosin (H&E) (C), and quantified (D).

Notes: (A) Black circles represent cells with fragmented DNA (apoptotic cells). Magnification, 40×. (C) Circles represent cells undergoing mitoses. Magnification: 20×. *Significance is set at P<0.05, and each value represents mean ± standard error of the mean; n=7 mice per group.