Table 5.

Differential diagnosis between tubular adenomas and tubular adenocarcinomas

Components	Tubular adenoma	Tubular carcinoma
Tubular structure	Present	Present
Lumen	Prominent	Present or absent
Secretion in lumen	Present	Present, in some cases prominent
Epithelium	Three cell types	Almost always one cell type
Cell morphology	Cuboidal, polarity preserved	Pleomorphic, loss of polarity
Nuclear features	Round shape, small nucleus	Oval, enlarged, prominent nucleus
Stroma	Scanty, scarce	Scanty or absent