Table 3. Amino acid sequences of intracellular loop and C-terminal region peptides.
All listed peptides were linked with a TAT sequence (YGRKKQRRR). The numbers indicate the peptide location in the mPanx1 amino acid sequence. The CT1 peptide has previously been published to inhibit NMDA-mediated Panx1 opening (21).
Amino acid sequence (mPanx1) | |
---|---|
IL1 | 178-VGQSLWEISE-187 |
IL2 | 191-KYPIVEQYLK-200 |
CT1 | 305-RRLKVYEILPTFDVLH-318 |
CT2 | 381-IPTSLQTKGE-390 |
Scrambled IL2 | IYLYVEQKPY |