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IP deficiency increased the number of Treg and inducible Treg (iTreg) cells in the lung compared to WT mice subjected to the tolerance protocol. Mouse lungs were harvested 1 day after OVA challenge (day 18). Treg cells (CD4+CD25+FoxP3+) and iTreg (IL-10+CD4+CD25+FoxP3+) cells were determined by flow cytometry. * p<0.05, n=5 mice per group.
