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. 2015 Mar 13;9(3):e0003604. doi: 10.1371/journal.pntd.0003604

Fig 1. 7-keto-sempervirol is a diterpenoid phenol derived from Lycium chinense.

Fig 1

This compound possesses a diterpenoid (C20) (4 isoprene units) scaffold consisting of a single phenyl group, one hydroxyl group (red) and one carbonyl group (red). In light of Lipinski’s rule of 5 (RO5) [57], this compound only possesses one violation to the rule (log p > 5), however, three out of the four core rules are satisfied.