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. 2015 Mar 13;9(3):e0003604. doi: 10.1371/journal.pntd.0003604

Fig 8. The diterpenoid 7-keto-sempervirol induces damage, shortening and loss of adult Fasciola hepatica tegumental spines.

Fig 8

SEM images of adult F. hepatica 48 hr post-treatment with culture media containing DMSO (1% v/v) or 100 μM 7-keto-sempervirol. A) Normal fluke ventral surface architecture including oral sucker (OS) and ventral sucker (VS) is unaffected after cultivation with culture media containing 1% (v/v) DMSO. B) Fluke dorsal surface architecture is also unaffected after cultivation with culture media containing 1% (v/v) DMSO. C) Fluke ventral spine phenotype after cultivation with culture media containing 1% (v/v) DMSO. D) Dorsal spine sockets (ss) and folding (fo) after cultivation with 100 μM 7-keto-sempervirol. E) Ventral spines after cultivation with 100 μM 7-keto-sempervirol. F) Higher magnification of (ss) region outlined by black box in (D).