Table 2. Estimates of malaria indicators.
Category | Characteristic | Study Site | ||
---|---|---|---|---|
Walukuba | Kihihi | Nagongera | ||
Sample size | Number of participants selected for laboratory testing | 631 | 788 | 808 |
Number of participants selected for laboratory testing ≤ 40 years of age | 582 | 682 | 685 | |
Anemia testing | Mean hemoglobin g/dL (SD) | 12.6 (2.0) | 12.8 (1.8) | 12.6 (1.9) |
Mean hemoglobin g/dL children < 5 years (SD) | 11.3 (1.6) | 11.7 (1.5) | 10.9 (1.6) | |
Hemoglobin < 11 g/dL, n (%) | 110 (18.9%) | 89 (13.1%) | 119 (17.4%) | |
Hemoglobin < 11 g/dL children < 5 years, n/N (%) | 63/155 (40.7%) | 54/183 (29.5%) | 78/158 (49.4%) | |
Hemoglobin < 8 g/dL, n (%) | 7 (1.2%) | 4 (0.6%) | 3 (0.4%) | |
Blood smear results | Positive for any asexual parasitemia, n (%) | 71 (12.2%) | 87 (12.8%) | 331 (48.3%) |
Positive for any asexual parasitemia children 2–10 years, n/N (%) | 38/233 (16.3%) | 50/280 (17.9%) | 189/317 (59.6%) | |
Geometric mean parasite density/μL | 438 | 881 | 950 | |
P. falciparum infection a , n (%) | 67 (94.4%) | 85 (97.7%) | 326 (98.5%) | |
Positive for any gametocytes, n (%) | 15 (2.6%) | 13 (1.9%) | 102 (14.9%) | |
Seroprevalence b | AMA-1 seropositive, n/N (%) | 309/580 (53.3%) | 428/679 (63.0%) | 565/675 (83.7%) |
Median AMA-1 antibody titer (IQR) | 87 (19–452) | 209 (32–913) | 709 (182–1887) | |
AMA-1 seroconversion rate (95% CI) | 0.10 (0.09–0.12) | 0.17 (0.14–0.19) | 0.42 (0.36–0.49) | |
MSP1–19 seropositive, n/N (%) | 173/544 (31.8%) | 344/678 (50.7%) | 310/679 (45.7%) | |
Median MSP1–19 antibody titer (IQR) | 66 (40–170) | 101 (40–539) | 94 (41–458) | |
MSP1–19 seroconversion rate (95% CI) | 0.036 (0.031–0.043) | 0.089 (0.078–0.100) | 0.064 (0.057–0.073) |
aOnly including those positive for asexual parasites
b No serology results obtain in 16 subjects for AMA-1 and 48 subjects for MSP1–19