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. 2015 Mar 7;15:29. doi: 10.1186/s12935-015-0177-1

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© Cheng et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Plectin depletion enhanced Chang liver cell migration. Plectin siRNA-transfected Chang liver cells were transferred to trans-well migration insert, followed by 4 hour incubation as described in the section of “materials and methods”. Plectin-knockdown Chang liver cell (refer to as Plectin siRNA) significantly showed a higher level of cell migration. Data are presented as mean ± standard error obtained from three independent experiments, *** indicates p < 0.001. The migrated cell number of mock group was assumed as 100%. Cell migration of plectin-knockdown Chang liver cell is presented as the ratio to that of the mock group.