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Plectin-knockdown Chang liver cells possess distinct cell morphology and FAK activity. Plectin siRNA-transfected Chang liver cells were fixed and stained with anti-plectin and anti-FAK antibodies. Confocal micrographs demonstrated that plectin-knockdown Chang liver cells were polarized and with less regularity in cellular arrangement. More induced actin stress fibers (arrowheads) and higher FAK activity (arrows) were shown at the cell edges. Scale bar = 10 um.
