Fig 5. Generation of protective anti-Ft LPS IgM is dependent on TLR2 and inflammasome.

Cytokine levels were measured 6 days p.i. in BALF (A) or serum (B) of mice intranasally infected with 4x10³ CFU Ft LVS. (C) Anti-Ft IgM were measured on day 7 p.i. in serum of mice infected as in A. (D) Organ bacterial burdens were measured 6 days p.i. in the indicated mouse strains infected as in A. Data are expressed as mean + S.D. *p<0.05, **p<0.01. Unpaired t-test.