Table 2.

Suggested priorities for future studies of rATG induction in heart transplantation

Comparison	Heart transplant population	Key endpoints
rATG versus no induction	Sensitized patients	Rejection rate, de novo DSA development, AMR
rATG + delayed CNI (day 7) for 7 days versus IL-2RA induction or no induction	Patients with renal impairment	Rejection rate, renal function, need for dialysis early after TX
rATG + low-exposure CNI versus no induction + standard-exposure CNI	Standard cohort	Rejection, renal function, side effects, infections

AMR, antibody-mediated rejection; CNI, calcineurin inhibitor; DSA, donor-specific antibodies; rATG, rabbit antithymocyte globulin.