Table 3.
Clinical Outcomes at 12 Months
| Complete Revascularization (n = 150) |
IRA-Only Revascularization (n = 146) |
HR (95% CI) | p Value | |
|---|---|---|---|---|
| Time to first event | ||||
| MACE | 15 (10.0) | 31 (21.2) | 0.45 (0.24–0.84) | 0.009 |
| All-cause mortality | 2 (1.3) | 6 (4.1) | 0.32 (0.06–1.60) | 0.14 |
| Recurrent MI | 2 (1.3) | 4 (2.7) | 0.48 (0.09–2.62) | 0.39 |
| HF∗ | 4 (2.7) | 9 (6.2) | 0.43 (0.13–1.39) | 0.14 |
| Repeat revascularization | 7 (4.7) | 12 (8.2) | 0.55 (0.22–1.39) | 0.20 |
| All events | ||||
| All-cause mortality | 4 (2.7) | 10 (6.9) | 0.38 (0.12–1.20) | 0.09 |
| Recurrent MI | 2 (1.3) | 4 (2.7) | 0.47 (0.09–2.59) | 0.38 |
| Type 1 | 0 | 2 | ||
| Type 4b | 2 | 2 | ||
| HF | 5 (3.3) | 10 (6.9) | 0.47 (0.16–1.38) | 0.16 |
| Inpatient | 3 | 7 | 0.56 | |
| Post-discharge | 2 | 3 | ||
| Repeat revascularization | 8 (5.3) | 16 (11.0) | 0.46 (0.20–1.08) | 0.07 |
| Safety | ||||
| CV mortality | 2 (1.3) | 7 (4.8) | 0.27 (0.06–1.32) | 0.11 |
| Stroke | 2 (1.3) | 2 (1.4) | 0.95 (0.13–6.77) | 0.96 |
| Major bleed | 4 (2.7) | 7 (4.8) | 0.55 (0.16–1.87) | 0.34 |
| Contrast-induced nephropathy | 2 (1.4) | 2 (1.4) | 0.94 (0.13-6.75) | 0.95 |
Values are n (%) for occurrences of both first events and total events. Outcomes are shown according to MACE and individual components of MACE (death, MI, HF, and revascularization) at 12 months.
CI = confidence interval; CV = cardiovascular; HF = heart failure; HR = hazard ratio; MACE = major adverse cardiac event; other abbreviations as in Table 1.
∗
Of the 13 patients with failure events, 5 (4 in the IRA-only group and 1 in the complete revascularization group) subsequently died during the 12-month follow-up.