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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Hypertension. 2015 Feb 17;65(4):800–805. doi: 10.1161/HYPERTENSIONAHA.115.05166

Figure 4. Deletion of Cys18-Cys137 disulfide bond of AGT did not affect plasma cholesterol concentrations.

Figure 4

(A) Plasma total cholesterol concentrations at termination were measured using an enzymatic kit. Histobars are mean and error bars are SEM. N = 7 – 10/group. P = 0.59 by Kruskal-Wallis One way ANOVA on Ranks. (B) Plasma lipoprotein distributions were resolved by size exclusion chromatography. Circles and error bars are means ± SEM. WT represents wild-type AGT AAV, and C18S,C137S represents AGT in AAV vector with Cys to Ser mutation at 18 and 137 residues.