. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Pharm Res. 2014 Oct 18;32(4):1395–1406. doi: 10.1007/s11095-014-1542-9

Table III.

Stability studies of JS-K. Percent recovery of JS-K or P123/JS-K calculated at the indicated time points

Solution (time)	JS-K (% recovery ± SEM^*)	P123/JS-K (% recovery ± SEM^*)	p^**
RPMI 1640/10% FBS (60 min.)	23 ± 0.4	48 ± 4	0.0015
Human plasma (60 min.)	39 ± 1	59 ±1.5	0.012
Whole blood (10 min.)	0 ± 0	6 ± 0	0.0284
4 mM GSH (5 min.)	8.5 ± 4.6	51 ± 10.8	0.003

Average and SEM of at least two independent experiments.

^**

The Students t-test was used to obtain P values comparing both formulations. Results were considered statistically significant for P < 0.05.