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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Transl Stroke Res. 2015 Jan 13;6(2):148–155. doi: 10.1007/s12975-014-0379-1

Figure 1.

Figure 1

BGN protein in CADASIL and control brain. Immunohistochemical analysis of genetically-defined CADASIL brains (A and B) and matched controls (C) was performed on frontal cortex sections with antibody 4E1-1G7. Penetrating arteries (A, C) and leptomeningeal (B) vessels are shown. Magnification is at 400x. (D) Brain lysates were analyzed by immunoblotting with 4E1-1G7 and the core BGN protein band was quantified for CADASIL and control frontal cortex, normalized to tubulin levels. Protein was not treated with glycosidases. Difference were significant (p<0.05) for CADASIL samples versus controls.