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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Hypertension. 2015 Feb 17;65(4):896–902. doi: 10.1161/HYPERTENSIONAHA.114.04760

Figure 2.

Figure 2

Effects of tBHQ or si-RNA to Nrf-2 vs scrambled siRNA medium nitrite and intracellular NO activity over 24 hours. A and C, dose response; B and D effect of si-RNA to Nrf-2 vs. scrambled si-RNA in HRGECs. Si-SCR, scrambled si-RNA; Si-Nrf-2, Nrf-2-siRNA; open boxes, vehicle, solid boxes, tBHQ (20 µmol∙l−1 in Panels B and D for 24hr). Mean ± SEM (n=6 per group). Compared to vehicle: *P < 0.05; **P < 0.01 and ***P < 0.005. Compared to si-SCR: ††, P<0.01; †††, P<0.005