Table 6. Benefit of 6-weeks fluoxetine treatment in patients who responded to treatment and who had remission according 17-item Hamilton Rating Scale for Depression.
| 6-week event rate for depression (%) | ||||||
|---|---|---|---|---|---|---|
| Placebo group | Fluoxetine group | Relative risk (95% CI) P-value | Absolute risk reduction (%) (95% CI) | NNT 1 | Odds Ratio (95% CI) P-value | |
| Response to treatment (decrease of 50% or more in HRSD) | 88 | 59 | 0.66 (0.51–0.87) P = 0.0025 (protective) | 30 (13–47) | 3 | 0.19 (0.06–0.56) P = 0.0029 |
| Remission (7 or less points in HRSD) | 95 | 85 | 0.89 (0.77–1.02) P = 0.097 | 11 (-0.02–23) | 9 | 0.27 (0.05–1.39) P = 0.117 |
1NNT = number needed to treat.