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. 2015 Mar 13;9(3):e0003585. doi: 10.1371/journal.pntd.0003585

Fig 4. Protective role of ScaA or combined immunization against heterologous strain infection.

Fig 4

Mice (n = 5/group) were immunized with the indicated antigens and challenged intraperitoneally with 10 x LD50 (A) or 100 x LD50 (B) of O. tsutsugamushi. Mice were immunized with antigens from the Boryong strain and challenged with the indicated strains (BR: Boryong, KP: Karp, KT: Kato). p value and median survival are summarized in S3 Fig. *, p < 0.05; **, p < 0.01.