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. 2015 Mar 13;11(3):e1004050. doi: 10.1371/journal.pcbi.1004050

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© 2015 Guex et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — Dynamical models of treatments/receptors/cytokines interactions in ivdTEM. Inputs (treatments) and output (receptor and secreted soluble factors) are depicted in yellow and red respectively. Factors that were used as treatment and measured as output are depicted in orange. Combined treatments (network nodes i.e. AND) are represented as small pink circles. Stimulatory and inhibitory effects of single or combined treatments are depicted by black arrow-headed edges and green edges respectively. Circles and diamonds represent soluble factors and receptors respectively. All the links presented are provided in S4 Table. Boolean equations used for representing ivdTEM regulatory networks are provided in S6 Table.