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. 2015 Jan 8;6(2):1031–1048. doi: 10.18632/oncotarget.2671

Figure 5. NOX4 interplays with IL-6 to regulate A549 cell proliferation and survival in vitro.

Figure 5

(A) The effects of IL-6, P6, or siltuximab on the proliferation of NOX4-transfected A549 cells. Bars are mean ± SD from four independent experiments. *Significantly different from control, P < 0.05. #Significantly different from NOX4 group, P < 0.05. (B) The effect of IL-6 on the proliferation of NOX4-depleted A549 cells. Bars are mean ± SD from four independent experiments. *Significantly different from control, P < 0.05. #Significantly different from NOX4 shRNA group, P < 0.05. (C) The effect of IL-6 on cell apoptosis of NOX4-depleted A549 cells. Bars are mean ± SD from four independent experiments. *Significantly different from control, P < 0.05. #Significantly different from NOX4 shRNA group, P < 0.05.