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. 2014 Dec 31;6(2):1143–1156. doi: 10.18632/oncotarget.2732

Figure 5. Exposure of MCF-7 cells to mitoxantrone induces an increase in gene expression of the established lysosomal enzyme markers GNS and CTSD.

Figure 5

MCF-7 cells were exposed to various concentrations of mitoxantrone for 24 hr. Then, GNS (A) and CTSD (B) gene expression levels were determined using quantitative real time PCR. Statistical significance is denoted by *(p < 0.05) and **(p < 0.01).